Type II diabetes mellitus (T2DM) increases the risk of developing Alzheimer’s disease, but the reasons why are not fully understood. To reduce the risk for cognitive decline in those with T2DM and to identify possible intervention targets, it is essential to comprehend how T2DM affects the brain and cognition.
The Diabetes Brain Study aims to understand the relationship between metabolic and Alzheimer’s risk and brain measures in 200 Latino middle-aged adults, who face a higher risk for T2DM and AD than non-Latino whites. Participants will have blood tests, medical exams, memory tests, and MRI imaging to reveal how cognitive decline occurs in T2DM patients, with and without AD pathology, and to identify brain imaging biomarkers for future interventions.
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