ADRC | USC ADRC Goals

USC ADRC Progressive Aim

USC ADRC Responsiveness to National Alzheimer’s Project Act (NAPA) Initiatives

The overarching aims of the USC ADRC are aligned and responsive to the National Alzheimer’s Project Act (NAPA) inaugurated in 2011 and updated in December.

NAPA Goal & Title of Initiative

ADRC Goals

1. Prevent & Effectively Treat ADRD

2. Enhance Care Quality and Efficiency

3. Expand Support for People with ADRD

4. Enhance Public Awareness & Engagement

5. Improve Data to Track Progress

6. Accelerate Action to Promote Healthy Aging & Reduce Risk Factors For ADRD

Aim 1: Characterize factors that modify the effect of APOE 4 on cognitive decline and AD biomarkers.

Aim 2: Support local research in ADRD.

Aim 1: Support ALZ-NET research data collection for patients being clinically treated with Lecanemab and other anti-amyloid antibodies in the real world, with a focus on early detection of ARIA.

Aim 2: Leadership role in roll-out of digital cognitive assessment in the Keck Healthcare system.

Aim 1: Integrate multi-disciplinary team in ADRC clinical core and Neurology Memory Disorders Clinic.

Aim 2: Collaborate with Family Medicine in provision of neurological expertise to CMS GUIDE program.

Aim 2: Support inclusive research, through GeneScreen, with a focus on outreach to underserved groups in Los Angeles County, including those seen in the Department of Health Services. Share data with national networks such as ALZ-NET. Organize numerous educational events.

Aim 3: Participate in national database initiatives (NACC, SCAN, ADNI, NCRAD, NIAGADS, CLARiTI).

Aim 1: Characterize factors that modify the effect of APOE 4 on cognitive decline and on AD ATN(vi) biomarkers, with an emphasis on vascular, metabolic, and ethnic influences, in concert with the new Center for Personalized Brain Health (CPBH).