The Clinical Core works directly with research participants to collect the careful clinical information needed to understand Alzheimer’s disease and related dementias over time. The core follows participants longitudinally, helping researchers study changes in memory, thinking, health, biomarkers, and brain structure.

The Clinical Core also maintains a registry of people interested in participating in research and supports studies across USC and national research networks. Through this work, the core helps connect participants with research opportunities while building the high-quality data needed to improve diagnosis, prevention, and treatment.