The Neuropathology Core studies donated brain and nervous system tissue to provide the most definitive information about Alzheimer’s disease and related dementias. By examining tissue after death, researchers can better understand the biological changes that occur in the brain and how they relate to memory loss, cognitive decline, and other symptoms.

The core maintains a large and valuable tissue bank that supports research at USC and beyond. It also helps connect pathology findings with clinical, genetic, biomarker, and imaging data, giving scientists a more complete picture of disease mechanisms and progression.