The Administrative Core provides the leadership, administrative mechanisms and oversight to enable the USC ADRC to achieve its overall aims and foster core interactions of the center. The Administrative Core is dedicated in supporting the USC ADRC missions by providing clear communication channels, strategically allocating resources, carefully managing the budget, and consistently ensuring compliance with all regulatory and participant safety standards. The Administrative Core has 4 specific aims:

1) Guide the scientific direction of the ADRC around its three overarching scientific goals to recruit and follow a clinical cohort that is enriched for carriers of APOE ε4, promote local ADRD research at USC, and further national collaborations.

2) Coordinate fiscal, operational, and regulatory functions across all cores to ensure appropriate, optimal, and effective utilization of center resources.

3) Promote participation across all Cores in collaborative national research initiatives, including NACC, NCRAD, ADGC, ADNI, ACTC, DVCID, ACAD, SCAN, and CLARiTI, leveraging our metabolic, vascular disease, and neuroimaging expertise to clarify factors that modify the effect of APOE ε4 on cognitive decline and AD biomarkers.

4) Attract early-stage and new investigators, and Support Training and Education through mentorship, development projects (DP), seminars, and research symposia and provide public education on the importance of understanding and addressing genetic, metabolic and vascular risk profiles for brain health.