Healthier Vessels, Healthier Brain Study (HVHB)

Purpose of the HVHB Study

The purpose of this study is to learn how vascular risk factors , such as high blood pressure, cholesterol, and/or blood sugar, may also be related to increased risk for developing Alzheimer’s Disease. This study is designed to examine biological markers for Alzheimer’s Disease risk found in the blood and cerebral spinal fluid of individuals who have either a high or low levels of vascular risk factors. Because these risk factors can be treated, our goal is to use the knowledge gained from this study to design programs that may reduce the risk of developing Alzheimer’s Disease and may also aid in earlier detection.

Who is eligible for the HVHB study?

• Men and women 65 years old or older
• People with or without a history of high blood pressure, high cholesterol, and/or early diabetes mellitus (not on insulin)
• Speak English or Spanish

What will I be asked to do as part of the HVHB study?

Once enrolled, you will be asked to complete:

• Physical and neurological exams
• Cognitive testing (e.g., memory, attention)
• MRI scans of the brain
• Lumbar punctures for cerebral spinal fluid studies
• Blood tests

We will provide you and your primary care physician results of your memory testing, MRI scans, and CSF and blood studies at your request.

Study volunteers will receive a small financial compensation for their participation.

How do I learn more about the HVHB study?

Call either of the numbers below to set up a confidential screening phone interview:

   Lina D’Orazio, Ph.D. (323) 442-7680

   Maria Hernandez (323) 442-6845