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What Causes Alzheimer Disease?

By definition, all forms of Alzheimer disease share two features in common, namely the abnormal accumulation of two misfolded proteins: 1) beta-amyloid (a-beta) and 2) phosphorylated tau (p-tau). The accumulation of these proteins may result from either over-production in or decreased clearance from the brain.


Alzheimer Disease And Other Forms Of Dementia

AD is the most common, but not the only, cause of dementia. Other disorders of the brain, such as stroke, Parkinson disease, HIV, hypothyroidism may also cause a loss of memory and intellectual abilities. A comprehensive neurological evaluation is essential for proper diagnosis and treatment.


Mild Cognitive Impairment (MCI)

Mild cognitive impairment refers to the stage when persons are still able to compensate for loss of memory and intellectual abilities. Dementia refers to a loss of memory and intellectual ability which is severe enough to affect activities of daily living.