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DATA AND INFORMATICS CORE

Resources
The Data, Imaging and Informatics core tracks the flow of participants, imaging, and biospecimens across the Center. It works with the Clinical and Pathology Core to upload the Uniform Data Set (UDS) to the National Alzheimer Coordinating Center (NACC). It offers research investigators access to large imaging and clinical databases from ADNI, ADRC, Program Project, and other NIH funded research studies. The Data Core provides expert biostatistical consultation and analyses to ADRC and affiliated investigators, including clinical trials, projects, and pilot studies.

Leadership team

Arthur Toga, PhD., Leader

Dr. Toga has a career-long record of funding and publication in the analysis, modeling and atlasing of images obtained from many species including humans. Dr. Toga directs several national and international collaborative studies that involve multisite acquisition of data, coordination of analysis, and dissemination of data and results. The USC Institute for Neuroimaging and Informatics (INI) and his laboratory coordinates neuroimage analysis and related informatics activities with national and international collaborators and, as such, is a worldwide resource by virtue of these distributive activities. Dr. Toga has experience and expertise in local and wide area computer networks, data transmission, storage and archiving as well as data compression and scientific visualization.

Wendy Mack PhD., Lead Biostatistician

Dr. Mack has 25 years of extensive experience and expertise in directing biostatistical and data coordination activities for single-and multi-centered clinical trials and observational studies. These have included 9 NIH-funded, randomized clinical trials, three long-running, multi-cycle NIA-funded program projects, as well as the USC Clinical Translational Research Center. Dr. Mack’s own research focuses on hormonal and soy clinical trial interventions related to atherosclerosis and cognitive outcomes in postmenopausal women. She is co-director of the graduate education programs in Biostatistics and Epidemiology in the Department of Preventive Medicine. Dr. Mack serves as the lead biostatistician and database director for the ADRC.